Bei der Umsetzung von optisch reinem (-)-8c fielen sowohl 1Oc als auch 12 teilweisc racemisicrt bzw. epimerisiert an.
3-(Dimethylamino)-2,2-dimethyl-2H-azirin als Aib-Äquivalent: Synthese von Aib-Oligopeptiden
✍ Scribed by Daniel Obrecht; Heinz Heimgartner
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- German
- Weight
- 962 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Teilweise in vorlaufigen Mitteilungen beschrieben [I] [2], s. auch [3].
📜 SIMILAR VOLUMES
The syntheses of phenacyl N-(2,2-dimethyl-2H-azirin-3-yl)-L-prolinate and allyl N-(2,2-dimethyl-2H-azirin-3-yl)-L-prolinate are reported. Reactions of these 2H-azirin-3-amine derivatives with Z-protected amino acids have shown them to be suitable synthons for the Aib-Pro unit in peptide synthesis. A
**Reaction of 3‐Dimethylamino‐2,2‐dimethyl‐2__H__‐azirine with Barbituric Acid** The reaction of 3‐dimethylamino‐2,2‐dimethyl‐2__H__‐azirine **(1)** with barbituric acid **(4)** in dimethyl formamide at room temperature yields a mixture of several compounds. The two main products **5** and **6** ha
**Reaction of 3‐Dimethylamino‐2,2‐dimethyl‐2__H__‐azirine with Phenyl Isothiocyanate** In contrast to the reactions of 3‐dimethylamino‐2,2‐dimethyl‐2__H__‐azirine (**1a**) with various isothiocyanates, leading to thiazoline derivatives, the reaction of **1a** with phenyl isothiocyanate at room temp
Reaktionen von 3-(Dimethylamino)-2,2-dimethyl-2H-azirin (1) mit 5 5disubstituierten Barbitursauren. -Die Umsetzung von 1 mit den 5,5-disubstituierten Barbitursauren 5b-e in i-PrOH bei ca. 70" lieferte unter C0,-Entwicklung die 2-[5-(Dimethylamino)-4,4-dimethyl-4H-imidazol-2-yl]alkanamide 6 b 4 (Sche