Novel N-(2,2-Dimethyl-2H-azirin-3-yl)-L-prolinates as Aib-Pro Synthons.
β Scribed by Simon Stamm; Heinz Heimgartner
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 25 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
The synthesis of methyl (2S,4R)-4-(benzyloxy)-N-(2,2-dimethyl-2H-azirin-3-yl)prolinate ( 10), a novel 2Hazirin-3-amine (3-amino-2H-azirine), is described (Scheme 1). The reaction of methyl (2S,4R)-N-(2methylpropanoyl)-4-(benzyloxy)prolinate ( 7) with Lawesson reagent gave methyl (2S,4R)-4-(benzyloxy
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