234 Lack of apolipoprotein E-4 [APOE-4] effect in familial late-onset Alzheimer disease [AD] in the amish population
โ Scribed by J.L. Haines; J.B. Rimniler; C.C. Johnson; E. D'Hondt; E. Justice; M.L. Pritchard; C.E. Jackson; M.A. Pericak-Vance
- Book ID
- 117413895
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 154 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0197-4580
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A strong association has been described in cross-sectional studies between the ~4 allele of the apolipoprotein E and late-onset Alzheimer's disease (LOAD). This study addresses the relationship between disease progression and the ~4 allele in 6 2 sporadic LOAD (onset at age 70 and over) patients. Di
An increased frequency of the apolipoprotein E type 4 allele (APOE-4) has previously been associated with both late-onset sporadic and late-onset familial Alzheimer disease (AD) [