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A novel mutation in the apolipoprotein E gene (APOE*4 Pittsburgh) is associated with the risk of late-onset Alzheimer's disease

โœ Scribed by M.Ilyas Kamboh; Christopher E Aston; Jordi Perez-Tur; Emre Kokmen; Robert E Ferrell; John Hardy; Steven T DeKosky


Book ID
117477517
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
145 KB
Volume
263
Category
Article
ISSN
0304-3940

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โœ Ki, Chang-Seok; Na, Duk Lyul; Kim, Jong-Won; Kim, Hye Jin; Kim, Doh Kwan; Yoon, ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 12 KB ๐Ÿ‘ 2 views

Butyrylcholinesterase (BChE) as well as acetylcholinesterase has been suggested to be associated with Alzheimer's disease (AD). : Hum Mol Genet 6: 1933-1936] recently reported the synergism between the gene for the K variant of BChE (BCHE-K) and the 4 allele of apolipoprotein E (APOE 4) in late-onse