## Abstract magnified image 2‐Vinyl quinazoline 3‐oxides **6a, 6b** and **15a** are useful modular building blocks for the construction of a range of heterocycles with potential biological activity, from __o__‐[amidoalkenyl]aryloximes **5a, 5b** and **14a**, respectively, by cyclocondensation. Con
2-Vinyl Quinazoline 3-Oxides. Preparation from Acid Induced Cyclocondensation of 2-Acylaminoaryloximes.
✍ Scribed by Frances Heaney; Elaine Lawless
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 27 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
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Pteroylglutamic acid was labeled with deuterium by trifluoroacetic acid-catalyzed exchange with deuterium oxide. The product, pteroylglutamic acid-3',5'-H2, was selectively labeled with deuterium in the 4-aminobenzoyl portion of the molecule; there was no evidence for isotope incorporation at C or
## Abstract Tetrahydro‐2__H__‐pyrrolo[1,2‐__c__]quinazoline‐3‐ones are easily obtained from the Friedel‐Crafts cyclization of __N__‐arylaminomethyl pyroglutamic acids. This reaction occurrs __via__ an acyliminium salt formed by decarboxylation of the acid function.
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## Abstract magnified image A simple preparation of ethyl 2,5‐dimethylfuran‐3‐carboxylate (**3**), 2,5‐dimethylfuran‐3,4‐dicarboxylic acid (**4**), and diethyl 2,5‐dimethylfuran‐3,4‐dicarboxylate (**5**) by treatment of diethyl 2,3‐diacetylsuccinate (**2**) with aqueous HCl is reported. The reacti