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2-Phenylaspartic acid derivatives from .beta.-lactams

โœ Scribed by Martin, Tellis A.; Comer, William T.; Combs, Charles M.; Corrigan, John R.

Book ID
126081909
Publisher
American Chemical Society
Year
1970
Tongue
English
Weight
619 KB
Volume
35
Category
Article
ISSN
0022-3263

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Highly efficient oxazolone-derived reage
Highly efficient oxazolone-derived reagents for beta-lactam formation from beta-amino acids
โœ Takehisa Kunieda; Tomohisa Nagamatsu; Tsunehiko Higuchi; Masaaki Hirobe ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 242 KB

Based on a unique leaving ability of 2-oxazolone moiety, highly efficient reagents have been developed for the formation of B-lactam compounds from B-amino acids including a facile preparation of the penam, a basic skeleton of penicillins.