Highly efficient oxazolone-derived reagents for beta-lactam formation from beta-amino acids

✍ Scribed by Takehisa Kunieda; Tomohisa Nagamatsu; Tsunehiko Higuchi; Masaaki Hirobe

• Book ID: 104220217
• Publisher: Elsevier Science
• Year: 1988
• Tongue: French
• Weight: 242 KB
• Volume: 29
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)86712-x

✦ Synopsis

Based on a unique leaving ability of 2-oxazolone moiety, highly efficient reagents have been developed for the formation of B-lactam compounds from B-amino acids including a facile preparation of the penam, a basic skeleton of penicillins.