Highly efficient oxazolone-derived reage
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Takehisa Kunieda; Tomohisa Nagamatsu; Tsunehiko Higuchi; Masaaki Hirobe
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Article
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1988
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Elsevier Science
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French
โ 242 KB
Based on a unique leaving ability of 2-oxazolone moiety, highly efficient reagents have been developed for the formation of B-lactam compounds from B-amino acids including a facile preparation of the penam, a basic skeleton of penicillins.