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Conversion of amino acids to .beta.-lactam derivatives via cyclopropanone

โœ Scribed by Wasserman, Harry H.; Glazer, Edward

Book ID
125995256
Publisher
American Chemical Society
Year
1975
Tongue
English
Weight
298 KB
Volume
40
Category
Article
ISSN
0022-3263

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โœ Ruth L. Guyer; Charles W. Todd ๐Ÿ“‚ Article ๐Ÿ“… 1975 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 343 KB

A method for converting thiazolinone derivatives of amino acids to their thiohydantoin derivatives is described. Because this method proceeds through a thermally induced intramolecular rearrangement, the amide groups of glutamine and asparagine are not hydrolyzed. Special procedures are not required