𝔖 Bobbio Scriptorium
✦   LIBER   ✦

1α,25-Dihydroxy-3-epi-vitamin D3 a physiological metabolite of 1α,25-dihydroxyvitamin D3: Its production and metabolism in primary human keratinocytes

✍ Scribed by Norbert Astecker; G. Satyanarayana Reddy; Gerda Herzig; Georg Vorisek; Inge Schuster

Book ID
117462532
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
171 KB
Volume
170
Category
Article
ISSN
0303-7207

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

1α,25-Dihydroxy-3-Epi-vitamin D3, a natu
1α,25-Dihydroxy-3-Epi-vitamin D3, a natural metabolite of 1α,25-dihydroxyvitamin D3, is a potent suppressor of parathyroid hormone secretion
✍ A.J. Brown; C. Ritter; E. Slatopolsky; K.R. Muralidharan; W.H. Okamura; G.S. Red 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 130 KB 👁 1 views

1␣,25(OH) 2 D 3 is an important negative regulator of parathyroid hormone (PTH) gene transcription. In parathyroid cells, as in other target tissues, 1␣,25(OH) 2 D 3 is degraded by side chain oxidation by the inducible 24-hydroxylase. We have previously shown that one metabolite of this pathway, 1␣,

Metabolism of 3H-1α,25-dihydroxyvitamin
Metabolism of 3H-1α,25-dihydroxyvitamin D3 in cultured human keratinocytes
✍ Swapna Ray; Dr. Rahul Ray; Michael F. Holick 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 462 KB

In the present investigation we studied the metabolism of 1 cu,25-dihydroxy-[l P-3H]vitamin D3 (3H-1 ,25(OH),D3) in culture-grown human keratinocytes (CHK). O u r results showed that the cellular uptake of 3H-1,25(OH)2D3, upon incubation with CHK, occurred very rapidly; and it paralleled a decrease