✍ Scribed by Kevin M Brindle; Roderick Porteous; Iain D Campbell
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A simple method is presented to accurately determine 15 N-{ 1 H} NOEs in biomolecules in the presence of H(N)-water proton chemical exchange. Three measurements are required: one with nonselective proton saturation and two with different water saturation conditions to determine the equilibrium value
## Abstract Chemical exchange phenomena in NMR spectra reveal protein motions on microsecond to millisecond time scales that are associated with biological functions, including catalysis, ligand binding, allosteric conformational changes and protein folding. This review surveys solution NMR methods
## Abstract The ^15^N chemical shifts and ^1^H^15^N and ^13^C^15^N coupling constants of nine monolabelled indazoles were measured and assigned. The experimental values are discussed in terms of the indazolic and iso‐indazolic structures, and compared with literature data for other related hetero
## Abstract Non‐selective and selective versions of several proton‐detected 1D NMR experiments to be applied to ^15^N are proposed. Clean, artifact‐free 1D spectra are easily obtained by the effective coherence selection by pulsed‐field gradients and the attainable sensitivity is maximized using mo