## Abstract The preparations of nicotin[2′,4′,6,‐^2^H~3~]anilide, 4′‐Cl‐nicotin[2′,6′‐^2^H~2~]anilide, 4′‐X‐nicotin[ar‐^3^H]anilide, (X = H−, CH~3~‐, Cl‐ or No~2~‐) and[6‐^14^C]nicotin[ar‐^3^H]anilide are described.
1278. Deuterium and tritium exchange reactions of phenols and the synthesis of labelled 3,4-dihydroxyphenylalanines
✍ Scribed by Kirby, G. W. ;Ogunkoya, L.
- Book ID
- 120056503
- Publisher
- The Royal Society of Chemistry
- Year
- 1965
- Weight
- 1012 KB
- Category
- Article
- ISSN
- 0368-1769
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The H -antagonists, metiamide and cimetidine were labelled 2 with deuterium and tritium in the 2-position of the imidazole ring by the uncatalyzed exchange reaction with deuterium and tritium oxide at 100°C. The sulfur-35 labelled metiamide was prepared by an exchange reaction with elemental sulfur-
## Abstract 1′,2′‐Dehydroolivetol and its monomethyl ether, 5′‐bromoolivetol, and olivetol‐5,‐^2^H~3~, have been synthesized. Acid catalyzed condensation of the latter three compounds with p‐mentha‐2,8‐dien‐1‐ol gave 1′,2′‐dehydro‐Δ^8^‐THC methyl ether, 5′‐bromo‐Δ^8^‐THC, and Δ^9^‐THC‐5′‐^2^H~3~, r