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Synthesis of tritium- and deuterium-labeled 9-.beta.-D-arabinofuranosyladenine and the tritium-labeled 5'-monophosphate ester with increased metabolic stability

✍ Scribed by Baker, David C.; Haskell, Theodore H.

Book ID: 121863256
Publisher: American Chemical Society
Year: 1975
Tongue: English
Weight: 539 KB
Volume: 18
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm00244a022

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## Abstract The enzymatic synthesis of l‐tryptophan and its derivative 5′‐hydroxy‐l‐tryptophan labeled with deuterium and tritium at the α‐carbon position is reported. The mixture containing __S__‐methyl‐l‐cysteine, indole or 5‐hydroxyindole dissolved in deuteriated or tritiated water has been conv