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1,2-Shifts of Hydrogen Atoms in Aryl Radicals

✍ Scribed by Brooks, Michele A.; Scott, Lawrence T.


Book ID
126077026
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
164 KB
Volume
121
Category
Article
ISSN
0002-7863

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Evidence for a 1,2 Shift of a Hydrogen A
✍ Meinrad Kunz; JΓ nos RΓ©tey πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 English βš– 100 KB

An excellent substrate of methylmalonyl-CoA mutase, methylmalonyl-carba-(dethia) coenzyme A (methylmalonyl-CH(2)-CoA), was synthesized by a chemoenzymatic method and its alpha-proton was exchanged with deuterium by long-term incubation in deuterium oxide at pH 6.9. After addition of highly purified