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1-Benzyl-1,2,3,4-tetrahydroisoquinoline (1BnTIQ), An Endogenous Neurotoxin, Induces Dopaminergic Cell Death Through Apoptosis

✍ Scribed by Shaik Shavali; Manuchair Ebadi


Book ID
117330103
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
254 KB
Volume
24
Category
Article
ISSN
0161-813X

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1-Benzyl-1,2,3,4-tetrahydroisoquinoline,
✍ Shaik Shavali; Edward C. Carlson; John C. Swinscoe; Manuchair Ebadi πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 279 KB

## Abstract 1‐Benzyl‐1,2,3,4‐tetrahydroisoquinoline (1BnTIQ), an endogenous neurotoxin, is known to cause parkinsonism in rodents and nonhuman primates. The levels of 1BnTIQ in cerebrospinal fluid of patients with Parkinson's disease (PD) were reported to be three times higher than those in control