## Abstract The steroidal pseudo‐amino acids 3ã‐amino‐5β‐cholan‐24‐oic acid (2a), 12ã‐acetoxy‐3ã‐ammonia‐5β‐cholan‐24‐oic acid (2b), and 7ã,12ã‐diacetoxy‐3ã‐amino‐5β‐cholan‐24‐oic acid (2c) are used as rigid spacers in the backbone of the cyclic peptides cyclo(–2a–Phe‐Phe–)~2~ (1a), cyclo(–2b–Phe‐P
ω-Amino Acids in Peptide Design. Crystal Structures and Solution Conformations of Peptide Helices Containing a β-Alanyl-γ-Aminobutyryl Segment
✍ Scribed by Karle, I. L.; Pramanik, Animesh; Banerjee, Arindam; Bhattacharjya, Surajit; Balaram, P.
- Book ID
- 127135679
- Publisher
- American Chemical Society
- Year
- 1997
- Tongue
- English
- Weight
- 274 KB
- Volume
- 119
- Category
- Article
- ISSN
- 0002-7863
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📜 SIMILAR VOLUMES
Synthesis and conformational studies of a short linear peptide containing a pyrrole amino acid (1, Paa) and a furan amino acid (2, Faa), namely Boc-hGly-Faa-D-Pro-Gly-Paa-hGly-Faa-OMe (3), were carried out in which it was established that peptide 3 adopted a well-defined b-hairpin structure in DMSO-
The dehydro-residue containing peptides N-Ac-dehydro-Phe-L-Leu-OCH3 ( I ) and N-Acdehydro-Phe-NorVal-OCH, (11) were synthesized by the usual workup procedures. The peptides crystallize from their solutions in methanol in space group P6,: ( I ) a = b = 12.528(2) A, c = 21.653(5) A; (11) a = b = 12.53