Nonstandard Amino Acids in Conformational Design of Peptides. Helical Structures in Crystals of 5-10 Residue Peptides Containing Dipropylglycine and Dibutylglycine
✍ Scribed by Karle, Isabella L.; Balaji Rao, R.; Prasad, Sudhanand; Kaul, Ramesh; Balaram, P.
- Book ID
- 118269493
- Publisher
- American Chemical Society
- Year
- 1994
- Tongue
- English
- Weight
- 749 KB
- Volume
- 116
- Category
- Article
- ISSN
- 0002-7863
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📜 SIMILAR VOLUMES
The dehydro-residue containing peptides N-Ac-dehydro-Phe-L-Leu-OCH3 ( I ) and N-Acdehydro-Phe-NorVal-OCH, (11) were synthesized by the usual workup procedures. The peptides crystallize from their solutions in methanol in space group P6,: ( I ) a = b = 12.528(2) A, c = 21.653(5) A; (11) a = b = 12.53
## Abstract The crystal structures of two oligopeptides containing di‐n‐propylglycine (Dpg) residues, Boc‐Gly‐Dpg‐Gly‐Leu‐OMe (**1**) and Boc‐Val‐Ala‐Leu‐Dpg‐Val‐Ala‐Leu‐Val‐Ala‐Leu‐Dpg‐Val‐Ala‐Leu‐OMe (**2**) are presented. Peptide **1** adopts a type I′β‐turn conformation with Dpg(2)–Gly(3) at th