α,β-Dehydro-amino acid residues in the design of peptide structures. Molecular and crystal structures of two folded dehydro peptides
✍ Scribed by V. Busetti; M. Crisma; C. Toniolo; S. Salvadori; G. Balboni
- Book ID
- 118563220
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 461 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0141-8130
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📜 SIMILAR VOLUMES
The dehydro-residue containing peptides N-Ac-dehydro-Phe-L-Leu-OCH3 ( I ) and N-Acdehydro-Phe-NorVal-OCH, (11) were synthesized by the usual workup procedures. The peptides crystallize from their solutions in methanol in space group P6,: ( I ) a = b = 12.528(2) A, c = 21.653(5) A; (11) a = b = 12.53
The peptide BOC-L-Val-APhe-APhe-L-Val-OCH3 was synthesized by the azlactone method in solution phase, and its crystal and molecular structures were determined by x-ray diffraction method. Single crystals were grown by slow evaporation from a methanol/water solution at 6°C. The crystals belong to an