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Ψ[CH(CF3)NH]Gly-peptides: synthesis and conformation analysis

✍ Scribed by Molteni, Marco; Bellucci, Maria Cristina; Bigotti, Serena; Mazzini, Stefania; Volonterio, Alessandro; Zanda, Matteo

Book ID
118177840
Publisher
Royal Society of Chemistry
Year
2009
Tongue
English
Weight
507 KB
Volume
7
Category
Article
ISSN
1477-0520

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## Abstract Partially modified retro‐ (PMR) and retro‐inverso (PMRI) ψ[NHCH(CF~3~)]Gly peptides, a conceptually new class of peptidomimetics, have been synthesized in wide structural diversity and variable length by aza‐Michael reaction of enantiomerically pure α‐amino esters and peptides with enan