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Stereocontrolled Synthesis of ψ[CH(CF3)NH]Gly-Peptides.

✍ Scribed by Marco Molteni; Alessandro Volonterio; Matteo Zanda

Book ID
101955516
Publisher
John Wiley and Sons
Year
2004
Weight
48 KB
Volume
35
Category
Article
ISSN
0931-7597

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Synthesis, Structure and Conformation of Partially-Modified Retro- and Retro-Inverso ψ[NHCH(CF3)]Gly Peptides
✍ Alessandro Volonterio; Stefano Bellosta; Fabio Bravin; Maria Cristina Bellucci; 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 401 KB

## Abstract Partially modified retro‐ (PMR) and retro‐inverso (PMRI) ψ[NHCH(CF~3~)]Gly peptides, a conceptually new class of peptidomimetics, have been synthesized in wide structural diversity and variable length by aza‐Michael reaction of enantiomerically pure α‐amino esters and peptides with enan