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Stereocontrolled Synthesis of ψ[CH(CF3)NH]Gly-Peptides

✍ Scribed by Molteni, Marco; Volonterio, Alessandro; Zanda, Matteo

Book ID
115504121
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
72 KB
Volume
5
Category
Article
ISSN
1523-7060

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## Abstract Partially modified retro‐ (PMR) and retro‐inverso (PMRI) ψ[NHCH(CF~3~)]Gly peptides, a conceptually new class of peptidomimetics, have been synthesized in wide structural diversity and variable length by aza‐Michael reaction of enantiomerically pure α‐amino esters and peptides with enan