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κ-Opioid receptors in the substantia nigra pars reticulata mediate the U-50,488-induced locomotor activity of preweanling rats

✍ Scribed by R.L Collins; A.R Zavala; A Nazarian; S.A McDougall


Book ID
114134846
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
167 KB
Volume
119
Category
Article
ISSN
0165-3806

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✍ Sanders A. McDougall; Audrey L. Rodarte-Freeman; Arbi Nazarian 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 144 KB 👁 1 views

## Opioid receptor agonists (e.g.,488) increase the locomotor activity of preweanling rats, while the same drugs depress the locomotor activity of adults. Curiously, direct stimulation of dopamine (DA) D 2 -like receptors fully attenuates the U-50,488-induced locomotor activity of preweanling rats