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δEF1 represses BMP-2-induced differentiation of C2C12 myoblasts into the osteoblast lineage

✍ Scribed by Shuang Yang; Li Zhao; Juhua Yang; Dinggeng Chai; Ming Zhang; Jie Zhang; Xiaohui Ji; Tianhui Zhu


Book ID
106577060
Publisher
BioMed Central
Year
2007
Tongue
English
Weight
617 KB
Volume
14
Category
Article
ISSN
1021-7770

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## Abstract The effects of Osteogenic Protein‐1 (OP‐1, BMP‐7) on the differentiation of the pluripotent mesenchymal cell line, C2C12, were examined. OP‐1 at 50 ng/ml partially inhibited myotube formation in C2C12 cells, while OP‐1 at 200 ng/ml completely inhibited myotube formation and induced the