𝔖 Bobbio Scriptorium
✦   LIBER   ✦

γδ T-cell development

✍ Scribed by James P. Allison

Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
876 KB
Volume
5
Category
Article
ISSN
0952-7915

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✦ Synopsis

~6 T cells consist of multiple lineages of cells with distinct antigen receptor repertoires, tissue localization and function. Recent evidence suggests that the ordered appearance of these sublineages during development is a result of programed rearrangement of Vy-gene segments. It appears that the T-cell receptor repertoire, at least of the y6 T cells with invariant receptors, is the result of site-directed rearrangement and cellular selection does not play a major role.

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