Development of γδ T cells in the adult murine thymus
✍ Scribed by Michelle Zorbas; Roland Scollay
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 591 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0014-2980
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Recent findings suggest that mature T cells in the thymus may regulate the growth and differentiation of immature thymocytes. Here we use mathematical modeling and computer simulations to identify the thymocyte subsets that might serve as targets for regulation, and the processes that might be affec
## Abstract The origin and development of T cells bearing γ/δ T cell receptors (TcR) has been extensively studied in the mouse. By contrast, little is known about development patterns and diversity of the human γ/δ T cell lineage. To study therepertoire of human γ/δ^+^ T cells during T cell ontogen