𝔖 Bobbio Scriptorium
✦   LIBER   ✦

γ-Hydroxybutyrate (GHB) in Humans : Pharmacodynamics and Pharmacokinetics

✍ Scribed by SERGIO ABANADES; MAGI FARRÉ; MIREIA SEGURA; SIMONA PICHINI; DIEGO BARRAL; ROBERTA PACIFICI; MANUELA PELLEGRINI; FRANCINA FONSECA; KLAUS LANGOHR; RAFAEL De La TORRE

Book ID
111480184
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
346 KB
Volume
1074
Category
Article
ISSN
0890-6564

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Feasibility of D-glucuronate to enhance
Feasibility of D-glucuronate to enhance γ-hydroxybutyric acid metabolism during γ-hydroxybutyric acid toxicity: pharmacokinetic and pharmacodynamic studies
✍ Indranil Bhattacharya; Kathleen M. K. Boje 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 162 KB 👁 1 views

g-Hydroxybutyric acid (GHB) is a drug of abuse. Literature studies showed that d-glucuronate acts as an oxidative stimulator of GHB metabolism following in vivo GHB tracer doses. The present proof-of-concept study investigates if d-glucuronate enhances GHB metabolism and inhibits blood-brain barrier

Integrated pharmacokinetics and pharmaco
Integrated pharmacokinetics and pharmacodynamics of atropine in healthy humans II: Pharmacodynamics
✍ Peter H. Hinderling; Ursula Gundert-Remy; Olga Schmidliny; Günther Heinzel 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 829 KB

This study determined the kinetics of the effects of atropine on heart rate and saliva flow in three healthy male volunteers after intravenous administration of 1.35 and 2.15 mg of the drug. The pharmacokinetics of atropine and its primary metabolite, tropine, were determined simultaneously. Both th