γ-alkylation of α,β-unsaturated acids : A technique of stereospecific isoprenoid homologation
✍ Scribed by B.S. Pitzele; J.S. Baran; D.H. Steinman
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- French
- Weight
- 493 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4020
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📜 SIMILAR VOLUMES
Y-alkylation of the title compounds with primary alkyl iodides is possible only when both a'-protons are first ionized with excess lithium diisoproylamide. a) M. Cooke and R. Goswami, J. Am. Chem. c, \_, 99 642 (1977). --b) J. A. M. van den Goorbergh and A. van der Cen, Rec. Trav. Chim., 102, 393 (
a,@-Epoxy ketones 2\_, upon treatment with two equivalents of trialkylstannylmethyllithium 1, afforded cyclopropanols 2 as a single product in acyclic system, and a mixture of cyclopropanols 2 and methylene 1,2-diols 2 in cyclic system. Under acidic conditions, the cyclopropanols gave p,y-unsaturate