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β-Turn Mimetic: Synthesis of Cyclic Thioenamino Peptides

✍ Scribed by Pappo, Doron; Kashman, Yoel

Book ID
127272512
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
115 KB
Volume
8
Category
Article
ISSN
1523-7060

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📜 SIMILAR VOLUMES

Methodology for the synthesis of mimetic
Methodology for the synthesis of mimetics of peptide β-turns
✍ Michael Kahn; Barbara Chen 📂 Article 📅 1987 🏛 Elsevier Science 🌐 French ⚖ 183 KB

This letter describes a scenario which provides for the stereospecific intro uction of both the amino and carboxyl termini portion of a designed B-turn mimetic. Peptides and proteins are ubiquitously distributed in nature, and play critical roles in the regulation of virtually all biological process

The design and synthesis of mimetics of
The design and synthesis of mimetics of peptide β-turns
✍ Michael Kahn; Susanne Wilke; Barbara Chen; Kagari Fujita; Yu-Hwei Lee; Michael E 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 410 KB

The synthesis of an 11 membered ring bis-lactam, a system which is designed as a conformationally restricted mimetic of type I and type II beta-turns is described. Computer assisted molecular modeling was used to compare the predicted low energy conformers of the turn mimetic with idealized type I a