Arsenite stabilizes IκBα and prevents NF
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Dan D. Hershko; Bruce W. Robb; Eric S. Hungness; Guangju Luo; Per-Olof Hasselgre
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Article
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2002
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John Wiley and Sons
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English
⚖ 229 KB
## Abstract Recent studies suggest that sodium arsenite downregulates NF‐κB activity by inhibiting phosphorylation and subsequent degradation of IκBα. Many effects of sodium arsenite are secondary to induction of heat shock proteins. The role of the heat shock response in arsenite‐induced inhibitio