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α1-Antitrypsin deficiency • 2: Genetic aspects of α1-antitrypsin deficiency: Phenotypes and genetic modifiers of emphysema risk

✍ Scribed by DeMeo, D. L. (author);Silverman, E. K. (author)

Book ID
118264755
Publisher
BMJ Publishing Group
Year
2004
Tongue
English
Weight
233 KB
Volume
59
Category
Article
ISSN
0040-6376

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✍ Ying Wu; Richard C. Foreman 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 882 KB

The human serum protein u,-antitrypsin is the major source of antiprotease activity found in the blood. The protein is synthesised primarily by liver cells but, to a lesser extent, by at least one other cell type. Expression of the gene has provided a paradigm for studies on transcriptional regulati