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Association between heterozygous α1-antitrypsin deficiency and genetic hemochromatosis

✍ Scribed by Raimund Kaserbacher; Theresa Propst; Albert Propst; Ivo Graziadei; Gert Judmaier; Wolfgang Vogel


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
153 KB
Volume
18
Category
Article
ISSN
0270-9139

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✦ Synopsis


Mieli-Vergani G. Value of urinary copper excretion after penicillamine challenge in the diagnosis of Wilson's disease. HEPATOLOGY


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Primary hemochromatosis is a genetically determined autosomal recessive disorder characterized by the excessive accumulation of body iron, most of which is deposited in the parenchymal cells of various organs. a,-Antitrypsin deficiency is characterized among others by defective secretion of a,-anti

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synthesized in the liver and is regulated by a gene located Genetic hemochromatosis and a 1 -antitrypsin (AAT) on chromosome 14 for which several alleles have been dedeficiency are frequent in white populations. Conflictscribed. The most common allele, PiM, is associated with an ing data on the asso