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α-methylenation of lactones and esters zinc bromide-catalysed phenylthiomethylation of o-silylated enolates

✍ Scribed by Ian Paterson; Ian Fleming

Publisher
Elsevier Science
Year
1979
Tongue
French
Weight
144 KB
Volume
20
Category
Article
ISSN
0040-4039

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✦ Synopsis

The a-methylene unit of a-methylene lactones 2.

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## SwmnarY ZnBr2-catalysed phenylthloalkylatlon of ketene bls(trlmethylsllyl)acetals, obtalned from carboxyllc acids, with appropriate a-chlorosulphldes can be used to prepare y-and 6lactones O-Sllylated enolate chemistry has recently produced new and improved methods for forming carbon-carbon bon