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Zr(HSO4)4catalyzed one-pot strecker synthesis of α-amino nitriles from aldehydes and ketones under solvent-free conditions

✍ Scribed by A. R. Hajipour; Y. Ghayeb; N. Sheikhan


Book ID
113009443
Publisher
Iranian Chemical Society
Year
2010
Tongue
English
Weight
167 KB
Volume
7
Category
Article
ISSN
1735-207X

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## Abstract Uncatalyzed one‐pot, three‐component reactions of aldehydes, chiral α‐methylamines, and dimethyl phosphite under solvent‐free conditions were used for the diastereoselective synthesis of α‐amino phosphonates. The reactions proceeded with extremely high efficiency under mild conditions a