One-pot diastereoselective synthesis of α-aminonitriles from aldehydes, chiral amines, and trimethylsilyl cyanide under solvent-free conditions
✍ Scribed by A. Kazemeini; N. Azizi; M. R. Saidi
- Book ID
- 111463904
- Publisher
- SP MAIK Nauka/Interperiodica
- Year
- 2006
- Tongue
- English
- Weight
- 149 KB
- Volume
- 42
- Category
- Article
- ISSN
- 1070-4280
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📜 SIMILAR VOLUMES
## Abstract A straightforward and efficient method has been developed for the synthesis of α‐aminonitriles by combining aldehydes, amines and trimethylsilyl cyanide in the presence of a catalytic amount of thallium(III) chloride tetrahydrate (1 mol%) under solvent‐free conditions at room temperatur
## Abstract Uncatalyzed one‐pot, three‐component reactions of aldehydes, chiral α‐methylamines, and dimethyl phosphite under solvent‐free conditions were used for the diastereoselective synthesis of α‐amino phosphonates. The reactions proceeded with extremely high efficiency under mild conditions a