Zinc supplementation decreases hepatic copper accumulation in LEC rat
✍ Scribed by Blanca P. Esparza Gonzalez; Rodolfo Niño Fong; Candace J. Gibson; I. Carmen Fuentealba; M. George Cherian
- Book ID
- 111635648
- Publisher
- Humana Press Inc
- Year
- 2005
- Tongue
- English
- Weight
- 254 KB
- Volume
- 105
- Category
- Article
- ISSN
- 0163-4984
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The concentration of copper in the livers of Long‐Evans rats with cinnamon‐like coat color (LEC), in which hepatitis and then hepatomas develop spontaneously, was recently found to be abnormally high. Therefore, we examined the copper concentrations in the livers of LEC F~1~ backcrosses
The aim of this study was to discover possible mechanisms of hepatocarcinogenesis of the Long-Evans cinnamon (LEC) rat, a new mutant inbred strain that manifests severe jaundice and anemia a few months after birth. The animals have an abnormal accumulation of copper in the liver and a low level of c