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Zinc-Mediated Acylation and Sulfonation of Pyrrole and Its Derivatives.

โœ Scribed by J. S. Yadav; B. V. S. Reddy; G. Kondaji; R. Srinivasa Rao; S. Praveen Kumar


Book ID
101933866
Publisher
John Wiley and Sons
Year
2003
Weight
132 KB
Volume
34
Category
Article
ISSN
0931-7597

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Zinc-mediated acylation and sulfonation
โœ J.S. Yadav; B.V.S. Reddy; G. Kondaji; R. Srinivasa Rao; S. Praveen Kumar ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 162 KB

Pyrrole and its derivatives react smoothly with acid chlorides and sulfonyl chlorides in the presence of zinc metal in toluene at ambient temperature to afford the corresponding 2-acetyl and 2-sulfonyl pyrrole derivatives in high yields with high regioselectivity.