## Abstract ## Background: Zetaβassociated protein (ZAPβ70) expression has been associated with a less favorable prognosis in chronic lymphocytic leukemia (CLL). The role of ZAPβ70 in immature Bβcells is not well understood. Immature or precursor B lymphocytes (hematogones) often occur in clinical
ZAP-70 and Bcl-2 expression in B lymphoblastic leukemia cells and hematogones
β Scribed by Fiona E. Craig; Sara A. Monaghan; Urvashi Surti; Steven H. Swerdlow
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 944 KB
- Volume
- 82B
- Category
- Article
- ISSN
- 1552-4949
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The presence of BCL-2gene rearrangement has been detected also in cellular populations lacking the t(14;18) chromosomal translocation, such as B-lineage acute lymphobiastic leukemia (ALL) cells. It has been reported that overexpression of BCL-2 is related to resistance to glucocorticoid-induced apop
## Abstract ## Background: Zetaβchain associated protein of 70kDa (ZAPβ70) is the most promising surrogate marker for the immunoglobulin heavy chain variable region (IgV~H~) mutation status in Bβcell chronic lymphocytic leukemia (BβCLL). Crespo et al. proposed the detection of ZAPβ70 by flow cytom
The improvement of life quality (evaluated by the Oswestry Disability index), the pain relief using the visual analog scale and the changes in the neurological status are presented. Conclusion: Surgical treatment of multiple myeloma of the spine seems to be an effective method to relieve pain and im