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Yeast ATP-Binding Cassette Transporters Conferring Multidrug Resistance

โœ Scribed by Prasad, Rajendra; Goffeau, Andre


Book ID
118258377
Publisher
Annual Reviews
Year
2012
Tongue
English
Weight
1019 KB
Volume
66
Category
Article
ISSN
0066-4227

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Multidrug resistance mediated by the ATP
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Resistance to multiple natural product drugs associated with reduced drug accumulation in human tumor cells may be conferred by either the 170 kDa P-glycoprotein or the 190 kDa multidrug resistance protein, MRP. Both MRP and P-glycoprotein belong to the large and ancient ATP-binding cassette (ABC) s