Yawning is elicited by D2dopamine agonists but is blocked by the D1antagonist, SCH 23390
β Scribed by G. Serra; M. Collu; G. L. Gessa
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 431 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0033-3158
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Injections of the selective D, dopamine agonist bromocriptine (5.0 mg/ kg, IP) produced progressively stronger locomotion over 10 days of repeated testing. Concurrent treatment with either the D, antagonist SCH 23390 (0.01 or 0.1 mg/kg, IP) or the D, antagonist raclopride (0.1 or 1.0 mg/kg, IP) supp
The effects of the putative selective dopamine D-1 antagonist benzazepine SCH 23390 and of the selective dopamine D-2 antagonist Ro22-2586 on stereotypy induced by the selective D-2 agonist RU24213 were compared. RU24213 (0.5-15 mg/kg) dose-dependently induced stereo-typed behaviour characterised by