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Xylitol dehydrogenase mutants of Pachysolen tannophilus and the role of xylitol in d-xylose catabolism

โœ Scribed by R. Maleszka; L.G. Neirinck; A.P. James; H. Rutten; H. Schneider

Book ID
109312241
Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
194 KB
Volume
17
Category
Article
ISSN
0378-1097

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Considerable interest in the D-xylose catabolic pathway of Pachysolen tannophilus has arisen from the discovery thatthis yeast iscapableoffermenting D-xylosetoethanol. In this organism D-xylose appears to be catabolized through xylitol to D-xylulose. NADPH-linked D-xylose reductase is primarily resp

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Xylitol production is suppressed by D-glucose. We previously reported that the suppression was abrogated in the presence of NaCl. This was explained in part by high levels of xylose reductase (XR) activity. In this study, we investigated the effects of D-glucose on XR and xylitol dehydrogenase (XDH)