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Xanthene derived potent nonpeptidic inhibitors of recombinant human calpain I

✍ Scribed by Sankar Chatterjee; Mohamed Iqbal; James C. Kauer; John P. Mallamo; Shobha Senadhi; Satish Mallya; Donna Bozyczko-Coyne; Robert Siman

Book ID: 104364626
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 230 KB
Volume: 6
Category: Article
ISSN: 0960-894X
DOI: 10.1016/s0960-894x(96)00286-7

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✦ Synopsis

Novel and potent, xanthene derived reversible aldehyde (7c) and a-ketocarboxamide (10a), and irreversible fluoromethyl ketone (10b) inhibitors of recombinant human calpain I are described.

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