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Nonpeptidic inhibitors of recombinant human calpain I

โœ Scribed by Sankar Chatterjee; Shobha Senadhi; Donna Bozyczko-Coyne; Robert Siman; John P. Mallamo

Book ID
104364821
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
182 KB
Volume
7
Category
Article
ISSN
0960-894X

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โœฆ Synopsis

The syntheses and biological activities of novel nonpeptidic calpain inhibitors 2-3, 12, and 14, derived from 2-naphthalenethiol, are described.

๐Ÿ“œ SIMILAR VOLUMES

Xanthene derived potent nonpeptidic inhi
Xanthene derived potent nonpeptidic inhibitors of recombinant human calpain I
โœ Sankar Chatterjee; Mohamed Iqbal; James C. Kauer; John P. Mallamo; Shobha Senadh ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 230 KB

Novel and potent, xanthene derived reversible aldehyde (7c) and a-ketocarboxamide (10a), and irreversible fluoromethyl ketone (10b) inhibitors of recombinant human calpain I are described.