X-Ray structures of endo and exo isomers of 6-tert-butyl-2-piperidone-4,5-(n-phenyldicarboximide)
β Scribed by B. Tinant; J. Feneau-Dupont; J. P. Declercq; P. Nshimyumukiza
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Weight
- 173 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0037-9646
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π SIMILAR VOLUMES
In a search for cytotoxic fluorescent ma- terials, a series of N-phosphorylated compounds 2a-c were prepared by phosphorylation of 3,5-bis(4-N,Ndimethylbenzylidene)-4-piperidone 1. According to X-ray investigations, molecule 2a is E,E-isomer with axial position of the P(O)(OCH 2 CF 3 ) 2 substituent
## Abstract The title compound **1** is a further example of an olefinic alcohol that undergoes ether formation under basic conditions **(β 3)** although the double bond is not activated by an electronβattracting group. This unusual reactivity is due to steric compression, which is increased in the