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## Abstract Two human gammaβherpesviruses, EpsteinβBarr virus and Kaposi's sarcoma associated herpesvirus/human herpesvirus 8 display oncogenic potential, causing benign and malignant lymphoproliferative disorders in genetically susceptible or immunosuppressed individuals. As a family of viruses th
T he development of immune defense mecha- nisms begins early during fetal life but is not completely achieved at birth, leading to a peculiar susceptibility of the neonate to infectious diseases. 1,2 The earliest hematopoietic stem cells are detectable in the yolk sac around 6 weeks of gestation, bu
## Abstract Β© 2005 Wiley Periodicals, Inc. J Biochem Mol Toxicol 19:177β179, 2005; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/jbt.20075
We have summarized current knowledge on the aging of the immune system in three vertebrate groups: fish, amphibians and birds. Available data are few due to difficulties in studying ageing in natural populations and in accurately determining age. In all vertebrates, the most obvious evidence of the