𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Aging of the vertebrate immune system

✍ Scribed by Marta Torroba; Agustín G. Zapata

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
66 KB
Volume
62
Category
Article
ISSN
1059-910X

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✦ Synopsis

We have summarized current knowledge on the aging of the immune system in three vertebrate groups: fish, amphibians and birds. Available data are few due to difficulties in studying ageing in natural populations and in accurately determining age. In all vertebrates, the most obvious evidence of the senescence of lymphoid tissue is the involution of thymus, which courses with decreased numbers of thymocytes, and loss of the histological organization of gland. On the other hand, there is little information on aged secondary lymphoid organs. Possible influence of the endocrine system in the changes observed in aged lymphoid organs is also discussed.

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