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Wolff-Kishner reduction of 8,9-dehydro-2-adamantanone

✍ Scribed by Murray, Roger K.; Babiak, Kevin A.


Book ID
127341730
Publisher
American Chemical Society
Year
1973
Tongue
English
Weight
287 KB
Volume
38
Category
Article
ISSN
0022-3263

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πŸ“œ SIMILAR VOLUMES


Synthesis of 8,9-dehydro-2-adamantanone
✍ Roger K. Murray Jr.; Kevin A. Babiak πŸ“‚ Article πŸ“… 1974 πŸ› Elsevier Science 🌐 French βš– 138 KB

8,9-Dehydro-2-adamantanone (1) has been shown to be a useful precursor for the synthesis of adamantyl,ly2 protoadamantyl,314 and isotwisty14 derivatives. However, it has not been convenient to employ (1) in synthesis, as the only reported preparation of (1) involves a multi-

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Wolff-KishneG carbmyl; tiuctiolc anionic cyclizalion; free rxlical cyclization Abstnact: The observation lhar Wo@Kishner reduction o/a &e-waturated ketone leads to the Irons cyclized product supports the proposed intermediacy of a m&anion in rhis reaction.