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Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells

✍ Scribed by Sheng-Teng Huang; Chen-Yu Wang; Rong-Chi Yang; Chih-Ju Chu; Hsiao-Ting Wu; Jong-Hwei S. Pang


Book ID
113848561
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
480 KB
Volume
17
Category
Article
ISSN
0944-7113

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Some widely used antidepressants such as imipramine, clomipramine, and citalopram have been found to possess antineoplastic effects. In the present study, these compounds were found to induce apoptotic cell death in human acute myeloid leukemia HL-60 cells. Apoptosis induced by the antidepressants w