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Nucleophosmin/B23 regulates the susceptibility of human leukemia HL-60 cells to sodium butyrate-induced apoptosis and inhibition of telomerase activity

โœ Scribed by Wen H. Liu; Chen Y. Hsu; Benjamin Y.M. Yung


Publisher
John Wiley and Sons
Year
1999
Tongue
French
Weight
207 KB
Volume
83
Category
Article
ISSN
0020-7136

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Berberine-induced apoptosis of human leu
โœ Hsing L. Wu; Chen Y. Hsu; Wen H. Liu; Benjamin Y.M. Yung ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 145 KB ๐Ÿ‘ 1 views

The steady-state level of nucleophosmin/B23 mRNA decreased during berberine-induced (25 microg/ml, 24 to 96 hr) apoptosis of human leukemia HL-60 cells. A decline in telomerase activity was also observed in HL-60 cells treated with berberine. A stable clone of nucleophosmin/B23 overexpressed in HL-6