Wnt-4 regulation by the Wilms' tumour suppressor gene, WT1
โ Scribed by Sim, Edmund U-H; Smith, Aaron; Szilagi, Elida; Rae, Fiona; Ioannou, Panos; Lindsay, Megan H; Little, Melissa H
- Book ID
- 110066569
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 419 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0950-9232
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Antisense transcripts are typically associated with the down-regulation of gene expression. In this issue, Moorwood et al. present evidence that an antisense RNA can enhance expression of the Wilms' tumour suppressor locus WT1. We suggest that the unusual function of the WT1 antisense RNA might rela
## Abstract This study reports on the evaluation of the Wilms tumor suppressor gene __WT1__ in 14 endometrial carcinomas. Despite the fact that several endometrial carcinomas were shown to express __WT1__, we were unable to demonstrate mutations in the __MT1__ zinc finger region, suggesting that __