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Wittig reaction: A new route to α-methoxyketones. Application to the synthesis of simplified analogs of artemisinin

✍ Scribed by Mohamed Hamzaoui; Olivier Provot; Boris Camuzat-Dedenis; Henri Moskowitz; Joëlle Mayrargue; Liliane Cicéron; Frédérick Gay


Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
122 KB
Volume
39
Category
Article
ISSN
0040-4039

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A simplified route to the synthesis of n
✍ Julien Le Gal; Eric Benoist; Marie Gressier; Yvon Coulais; Michèle Dartiguenave 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 175 KB

The synthesis of two new N 2 S 2 or N 2 SO tetradentate ligands and the preparation of their technetium-99m complexes are reported. Each ligand leads to a unique 99m Tc-complex with an excellent radiochemical yield. The in vivo stability of these complexes was determined by serum stability and cyste